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Factor XIII, an enzyme that cross-links fibrin, belongs to the blood coagulation system. Screening for factor XIII, also known as fibrin-stabilizing factor, is performed when its absence is suspected. Qualitatively, factor XIII levels are referred to as decreased or normal.
Overnight fasting is required. Before to sampling, it is advised that the patient stop using oral anticoagulants for seven days and heparin for one day, respectively. Discontinuation should only be done with the treating physician permission.