Download Icon

Use App for best experience!

Available for Android & iOS

Popular Tests
    Top test not found
Popular Packages
    Top test not found
  • playstore
  • app store
play store

Popular Tests
    Top test not found
Popular Packages
    Top test not found
Test
test details

KRAS MUTATION DETECTION (O.S)

MRP: ₹6200

Recommended For

maleMalefemaleFemale
  • Age Group
    Age Group0-99 Years
  • Report Generation Time
    Report Generation Time12-04-2024 08:39:53
  • Sample Type
    blood sampleBlock
  • Collection At
    home visitHomelab flaskLab
Description

KRAS somatic mutations are found in 30-40% of colorectal cancer (CRC). Seven mutations in codons 12 and 13 of KRAS (95% of the observed human mutations) preclude the efficacy of anti-EGFR therapy for the treatment of CRC. Assessment of KRAS mutational status has become a standard procedure in the management of patients with CRC. Technically, KRAS mutation testing can be performed with different methods, characterized by distinct sensitivities and specificities. Strategies that focus on early detection and prevention effectively decrease the risk of mortality associated with cancer. In addition, an increase in survival rate for individuals with advanced stage disease has been observed as a result of advancements in standard chemotherapeutic agents and the development of specialized targeted therapies. Monoclonal antibodies against epidermal growth factor receptor (EGFR), such as cetuximab and panitumumab, represent an area of targeted therapy for patients with colorectal and non-small cell lung cancer (NSCLC). This test uses DNA extracted from tumor tissue to evaluate for the presence of KRAS (G12A, G12C, G12D, G12R, G12S, G12V, G13D, Q61K, Q61L, Q61R, Q61H, and A146T) variants. A positive result indicates the presence of an activating KRAS mutation and can be a useful marker by which patients are selected for EGFR-targeted therapy.

Pre-Information

Biopsy specimen / paraffin block required for this test.

You can also add

ADVANCE HEART SECURE PROFILE*

1190

Add

VITAL SURAKSHA PACKAGE*

650

Add

SPECIAL SURAKSHA PACKAGE*

1590

Add

COMPLETE SURAKSHA PACKAGE*

2990

Add

DIABETES SURAKSHA PACKAGE*

1590

Add

Dr. B. Lal Mobile App

Simple Hai
Download, Karke Dekho
  • Easy to book & time saving
  • Access your previous test reports & invoices
  • Track your entire sample journey from booking to report generation
  • View your reports smartly- See trend analysis of your health parameters
  • Stay up to date with our personalized health tips & Bulletin

Available on:

playStoreappStore
© Copyright 2022 - Dr. B. Lal Clinical Laboratory Pvt. Ltd. All Rights Reserved.