AMH-MULLERIAN INHIBITING SUBSTANCE

Overview

Anti-Müllerian hormone (AMH) is produced by immature Sertoli cells in the male and in granulosa cells in preantral and small antral follicles in the female. AMH is used for the evaluation of ovarian reserve and prediction of the outcome of Assisted Reproductive Technology (ART). It can also be used to assess ovarian function in patients with Polycystic Ovarian syndrome, menopausal status and to diagnose and monitor Ovarian Granulosa cell tumor. AMH measurements can also be used to evaluate testicular presence and function in infants with intersex conditions or ambiguous genitalia, and to distinguish between Cryptorchidism (testicles present but not palpable) and Anorchia (testicles absent) in males.