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Test
test details

ZnT8 (ZINC TRANSPORTER 8) ANTIBODY (O.S)

MRP: ₹4500

Recommended For

maleMalefemaleFemale
  • Age Group
    Age Group0-99 Years
  • Report Generation Time
    Report Generation Time
  • Sample Type
    blood sampleSerum
  • Collection At
    home visitHomelab flaskLab
Description

Zinc transporter 8 (ZnT8) is an islet beta-cell secretory granule membrane protein recently identified as an autoantibody antigen in Type 1 Diabetes. ZnT8 autoantibodies are present in around 65 to 80% of children with recently diagnosed Type 1 Diabetes and 20% to 40% of adults with Type 1 diabetes. ZnT8 antibody complements GAD-65, IA-2, and insulin antibodies as it is positive in 3% to 4% of patients who are negative for GAD-65, IA-2, and insulin antibodies. Use of these 4 antibodies results in 93% to 98% sensitivity. ZnT8 antibody testing can be considered for clinical distinction of Type 1 from Type 2 Diabetes Mellitus, identification of individuals at risk of Type 1 Diabetes (including high-risk relatives of patients with diabetes, and those with Gestational Diabetes) & prediction of future need for insulin treatment in adult-onset diabetic patients.

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