C-erb-B2 / Her2 Neu (IHC)

Requirements

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    Sample Required Tissue

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    Preperations Required Provide a copy of the biopsy site, histopathology report, and clinical history.

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    Gender Male & Female

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    Age Group 0 - 99 Years

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    Collection AtHome & Lab

2090
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    1 Observations included

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C-erb-B2 / Her2 Neu (IHC)

Observations Included

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10,000+ Tests Done

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Trusted By Doctors

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NABL Certified Labs

Overview

HER2 (ERBB2: c-erb-b2) is an oncogene located on the long arm of chromosome 17 and is amplified in approximately 15% to 20% of breast cancers. Amplification or overexpression of HER2 is associated with shorter disease-free survival and poorer overall survival in breast cancer patients. Patients with HER2 gene amplification or overexpression are candidates for treatment with drugs that target the human epidermal growth factor receptor 2 (HER2) protein or its downstream pathways, such as trastuzumab (Herceptin) and pertuzumab.

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