The Endomysial Antibody (EMA) IgA test is a specific marker used primarily to screen for celiac disease, an autoimmune condition triggered by gluten. This test detects IgA antibodies targeting endomysial tissue in the intestines, which are typically elevated in individuals with untreated celiac disease. A positive EMA IgA result, especially when combined with symptoms and other diagnostic findings, strongly suggests celiac disease. It is recommended for patients presenting with gastrointestinal symptoms, malabsorption issues, or family history of celiac disease.