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This assay is useful in the investigation of Primary Aldosteronism (Adrenal Adenoma / Carcinoma and Adrenal Cortical Hyperplasia) and Secondary Aldosteronism (Renovascular disease, salt depletion, potassium loading, cardiac failure with ascitis and pregnancy).
Two hours before the sample is taken, the patient should be ambulatory and upright. Medication interactions should be ceased at least for 4 weeks. Any drug modification should be made after consulting the prescribing physician.