SS-B/La is an extractable nuclear antigen with antibodies occuring in patients with Sjogrens syndrome (60%) & Lupus erythematosus (15%). Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive. A positive result for SS-B/La antibodies is consistent with connective tissue disease, including Sjogren syndrome and lupus erythematosus