The major electrolytes: sodium, potassium, and chloride..These are substances that have a natural positive or negative electrical charge when dissolved in water. They help our body in regulating chemical reactions, maintain the balance between fluids inside and outside your cells. Electrolyte panel is useful in assessing acid base balance in a wide variety of medical conditions.Common symptoms of electrolyte imbalance include irregular heartbeat, confusion, fatigue, lightheadedness, blood pressure changes, muscle weakness or twitching, numbness and seizures.