APTT Mixing study (O.S)

Requirements

Sample Required SODIUM CITRATE PLASMA
Preperations Required Overnight fasting is preferred. 6 mL Whole blood in 2 Blue Top (Sodium Citrate) tubes. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.
Gender Male & Female
Age Group 0 - 99 Years
Collection AtHome & Lab

₹ 3000

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APTT Mixing study (O.S)

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Overview

A prolonged APTT indicates a potential issue with the intrinsic and common pathways of the coagulation cascade, suggesting a clotting factor deficiency or inhibitor presence. The mixing study helps differentiate between these possibilities. Correction of a prolonged APTT with mixing generally implies a qualitative or quantitative abnormality of one or more clotting factors in the patient plasma. In contrast, failure of APTT to correct completely on mixing suggests the presence of inhibitor in the patient plasma eg. Lupus anticoagulants & inhibitors to specific clotting factors.6 mL Whole blood in 2 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to the Lab within 4 hours. If this is not possible, prepare PPP within 1 hour of collection as follows: Prepare PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 mins. & finally transfer the supernatant (PPP) to 1 labelled, clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW.