MYASTHENIA GRAVIS PANEL (O.S)

Overview

Myasthenia gravis (MG) is a neuromuscular junction disorder characterised by muscle weakness & easy fatigability most commonly due to autoantibody mediated loss of functional acetylcholine receptors in the postsynaptic membrane of skeletal muscle. MG has a prevalence of 200 in 100,000 affecting all age groups but peak incidence is in women in 20 to 30 years age group. Men are less frequently affected and are usually in 50 to 60 years age group. Course of MG is variable with remissions & exacerbations specially during first few years after onset of disease. Ptosis & diplopia are common symptoms.