APTT-ACTIVATED PARTIAL THROMBOPLASTIN TIME

Requirements

Sample Required SODIUM CITRATE PLASMA
Preperations Required Overnight fasting is preferred. 6 mL Whole blood in 2 Blue Top (Sodium Citrate) tubes. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.
Gender Male & Female
Age Group 0 - 99 Years
Collection AtHome & Lab

₹ 400

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APTT-ACTIVATED PARTIAL THROMBOPLASTIN TIME

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Overview

The activated partial thromboplastin time (APTT) measures the integrity of the intrinsic (factors VIII, IX, XI and XII) and common (factors II, V, X, and I fibrinogen pathway.A prolonged APTT may be caused by congenital or acquired coagulation factor deficiencies, anticoagulant effect such as heparin anticoagulation therapy, and inhibition due to lupus anticoagulants as well as other nonspecific coagulation inhibitors .Shortening of the APTT usually reflects either elevation of factor VIII activity secondary to acute or chronic illness or inflammation, or spurious results from suboptimal venipuncture, specimen collection or processing.