ROS 1 Rearrangement FISH (O.S)

Requirements

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    Sample Required BLOCK

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    Preperations Required Biopsy specimen / paraffin block required for this along with histopathology report is mandatory.

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    Gender Male & Female

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    Age Group 0 - 99 Years

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    Collection At Lab

13100
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    1 Observations included

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    Results with in 21 Hours

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ROS 1 Rearrangement FISH (O.S)

Observations Included

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10,000+ Tests Done

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Trusted By Doctors

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NABL Certified Labs

Overview

Identifying c-ros oncogene 1 (ROS1) gene rearrangements in patients with late-stage, lung adenocarcinomas that are negative for epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements. Lung cancer is the leading cause of cancer mortality in developed countries. The discovery of a variety of genetic alterations in non-small-cell lung cancer (NSCLC) has enabled the use of targeted therapy such as the anaplastic lymphoma kinase (ALK) inhibitor, crizotinib, and the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, erlotinib, for NSCLC with ALK rearrangements and EGFR mutations, respectively. Identifying c-ros oncogene 1 (ROS1) gene rearrangements in patients with late-stage, lung adenocarcinomas that are negative for epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements

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