SLA (SOLUBLE LIVER ANTIGEN) (O.S)

Overview

Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays. Reference Range: Negative 0.0-20.0 U, Equivocal 20.1-24.9 U, Positive >25.0 U