Congenital Syphilis Screen, (IgG, IgM) - This panel detects both IgG and IgM Antibodies to T. pallidum, the causative agent of syphilis. Its intended use is to differentiate fetal from maternal antibody in cases of suspected congenital syphilis infection. Both IgG and IgM antibodiesare detected in plasma from patients with untreated primary syphilis. IgM reactivity declined rapidly and uniformly after therapy, whereas IgG persisted despite some diminution in intensity of staining.