Overview
Anti-Müllerian hormone (AMH) is produced by Sertoli cells in males and granulosa cells in females, serving as a key marker for assessing ovarian reserve and predicting outcomes in Assisted Reproductive Technology (ART). It also aids in evaluating ovarian function in Polycystic Ovarian Syndrome and diagnosing conditions like Ovarian Granulosa Cell Tumors and testicular issues in infants.
What is the AMH Test ?
Anti-Müllerian Hormone (AMH) is produced by immature Sertoli cells in the male and in granulosa cells in preantral and small antral follicles in the female. AMH is used for the evaluation of Ovarian reserve and prediction of the outcome of Assisted Reproductive Technology (ART). It can also be used to assess Ovarian function in patients with Polycystic Ovarian Syndrome, menopausal status and to diagnose and monitor Ovarian Granulosa Cell Tumor. AMH measurements can also be used to evaluate testicular presence and function in infants with intersex conditions or ambiguous genitalia, and to distinguish between Cryptorchidism (testicles present but not palpable) and Anorchia (testicles absent) in males.
What is the Purpose of the AMH Test ?
An AMH Test is generally advised in several circumstances, which are:
- Fertility Assessment: To assess an individual's ovarian reserve, particularly if she is planning a pregnancy or is having trouble getting pregnant. The amount of eggs left in the supply is estimated by AMH levels.
- In Vitro Fertilization (IVF) Planning: To predict the ovarian response to stimulation during IVF treatment and assist in determining the proper dosage of fertility drugs.
- Polycystic Ovary Syndrome (PCOS): Since elevated AMH levels are common in women with PCOS, the test can aid in both diagnosis and condition monitoring.
- Premature Ovarian Insufficiency (POI): To evaluate ovarian function because low AMH levels may be a sign of decreased ovarian reserve in women going through early menopause or irregular menstrual cycles.
- Oncology and Chemotherapy Planning: The AMH test can assist in determining the possible effects on fertility for women receiving cancer treatment, particularly Chemotherapy or Radiation, which can affect Ovarian function.
- Assessing Menopause Timing: Deteriorating AMH levels indicate the onset of perimenopause.
When is an AMH Test Recommended ?
If you have following symptoms or conditions, then AMH Test is advised:
- Irregular or missed periods
- Difficulty in conceiving
- Polycystic Ovary Syndrome (PCOS)
- Early menopause symptoms such as ovarian insufficiency (POI) or early menopause, such as hot flashes or irregular cycles
- History of ovarian surgery
- Assess potential effects of planned cancer treatment like chemotherapy or radiation on ovarian function and fertility
- Family history of early menopause
Preparation for AMH Test
- There is no special preparation required before the AMH Test.
- Other blood tests can be carried out in addition to an AMH Test. If your doctor advises you to have multiple tests at once, they may ask you to fast for a specific period of time prior to a blood test.
- Drink adequate water before sample collection.
- Follow the preparatory instructions as guided by your doctor.
What is the Cost of an AMH Test ?
The Price of an AMH Test is Rs. 1500. However, cost of the test may fluctuate depending on following factors:
- Other tests advised along with AMH Test
- Offers or discounts
- Empanelment of the patient
Components of AMH Test
- AMH: Ovarian Follicles produce the Hormone AMH (Mullerian Inhibiting Substance), which aids in determining Ovarian reserve. Elevated AMH levels are often seen in Polycystic Ovary Disorder (PCOD Advanced Package), suggesting a greater number of Follicles and supporting the diagnosis and assessment of Fertility potential.
Interpreting the AMH Test Results
Healthy and Trying to Get Pregnant:
- High AMH Levels: Indicates a larger number of available eggs, suggesting a better ovarian reserve and fertility potential.
- Low AMH Levels: Indicates a reduced egg supply, which may shorten the time available for conception.
Polycystic Ovary Syndrome (PCOS):
- High AMH Levels: Suggests the presence of PCOS, although the test alone cannot diagnose the condition.
- Management: PCOS cannot be cured, but symptoms can be controlled with medications and/or lifestyle changes.
Menopause:
- Low AMH Levels: May indicate you are approaching Menopause, but it can't predict the exact timing of menopause.
- No AMH detected: Means you are in Menopause.
- Low AMH in Women under 40 with Menopause symptoms: Could indicate primary ovarian insufficiency.
Ovarian Cancer Treatment:
- Decrease in AMH: Generally indicates that Cancer treatment is working.
- Increase in AMH: May suggest that the treatment is ineffective or the Cancer has returned.
Undescended Testicles in Male Babies/Children:
- Normal AMH Levels: Indicates the baby has working testicles, though they are not in the correct location. This condition can be treated with Surgery and/or Hormone Therapy.
- Little or no AMH: May indicate that the testicles are non-functional or absent, possibly due to a genetic mutation, and the baby may have atypical internal Female reproductive organs.
Ambiguous Genitalia in Babies:
- The interpretation of AMH test results depends on the results of other tests in cases of ambiguous Genitalia, where the Baby’s sex characteristics are not clearly Male or Female.
How is the AMH Test Done ?
The Blood Sample for AMH Test is taken in following steps:
- The area where the needle will be inserted to take your Blood is cleaned with an Antiseptic Alcohol wipe. The hollow on the inside side of the Elbow or the tip of the Finger are the most common sites for this.
- A tourniquet or a band is tied around your upper arm to facilitate the access to the Vein in your Arm.
- A Needle is used to puncture your Vein. The Blood sample is collected into a test tube attached to the needle. The Needle may cause a small pinch or sting when it is inserted.
- Once the Vial or test Tube is filled, the Blood sample collection for the test is finished and the Needle is taken out.
- Finger pressure is applied on the puncture site to stop the bleeding and the Band aid is applied at the site.
How to Schedule an AMH Test with Dr. B. Lal Lab ?
- Go to the Dr. B. Lal Lab website.
- Go to the “Book a test” tab.
- Select the “Lab Test” tab.
- Type “AMH Test” in the search bar.
- Click on the test.
- The test page with all the test details will show up.
- Click on “Book Now”.
- Login and verify your mobile number with OTP.
- Now enter your details.
- Select date & time for booking AMH Test in Jaipur.
- Check out.