Overview
Apolipoprotein A1 (ApoA1) is important for assessing the risk of atherosclerotic cardiovascular disease and diagnosing Tangier disease. It plays a key role in reverse cholesterol transport, with higher ApoA1 levels more strongly associated with reduced risk of a first myocardial infarction than HDL-C concentrations. Additionally, low ApoA1 levels can predict preclinical atherosclerosis based on coronary artery calcium scoring.
What is the Apolipoprotein A1 Test ?
Apolipoprotein B (ApoB) is the primary protein component of low-density lipoprotein (LDL). Apolipoprotein A1 (ApoA1) is the primary protein component of high-density lipoprotein (HDL). Elevated ApoB and decreased ApoA1 are associated with increased risk of cardiovascular disease.
What is the Purpose of the Apolipoprotein A1 Test ?
This Test is advised for following assessments:
- Evaluate the Risk of Heart Diseases: Low levels of ApoA1 are associated with an increased risk of Cardiovascular diseases (CVD), such as Atherosclerosis and Coronary Artery Disease.
- Insight to HDL Functioning: It provides more detailed information about the quality and functionality of HDL Cholesterol compared to standard Lipid Panels.
- Diagnose and Monitor Lipid Disorders: Helps in diagnosing rare lipid metabolism disorders like Tangier disease and familial HDL deficiency.
- Monitor Effectiveness of Heart Treatments: Used to assess the effectiveness of lipid-lowering treatments, such as statins or lifestyle changes, in improving Cardiovascular health.
- Diagnosing the Inflammatory Conditions: ApoA1 levels may decrease in inflammatory states, providing additional clues in broader diagnostic contexts.
When is an Apolipoprotein A1 Test Recommended ?
The following are a few signs or conditions that could indicate the need for a Apolipoprotein A1 Test:
- Family History of Heart Disease
- Personal History of Early Heart Disease
- High Cholesterol Levels That Don’t Improve
- Atherosclerosis
- Unexplained Stroke or Heart Attack
- High Blood Pressure
- Chronic Kidney Disease
Preparation for Apolipoprotein A1 Test
- Unless otherwise directed by your doctor, there is no need for you to make any special preparations before the Apolipoprotein A1 Test.
- Other blood tests can be carried out in addition to a Apolipoprotein A1 Test. If your doctor advises you to have multiple tests at once, they may ask you to fast for a specific period of time prior to a blood test.
- Drink adequate water before sample collection.
- Avoid vigorous physical activity before the sample collection.
- Follow the preparatory instructions as guided by your doctor.
What is the Cost of the Apolipoprotein A1 Test ?
The Price of a Apolipoprotein A1 Test is ₹1375. However, cost of the test may fluctuate depending on following factors:
- Other tests advised along with Apolipoprotein A1 Test
- Offers or discounts
- Empanelment of the patient
Components of Apolipoprotein A1 Test
- Apolipoprotein A1: One of the proteins found in HDL ("good") Cholesterol is Apolipoprotein A. It aids in the beginning of the process for HDL to remove bad Cholesterol from your body. Apolipoprotein A can therefore help to reduce your risk of Cardiovascular disease.
Interpreting the Apolipoprotein A1 Test Results
The normal levels of Apolipoprotein A1 vary, but generally:
Normal Ranges:
- Men: 105–160 mg/dL (1.05–1.60 g/L)
- Women: 110–180 mg/dL (1.10–1.80 g/L)
- Children: 108–203 mg/dL (1.08–2.03 g/L)
Key Points:
Higher Levels:
- Indicative of good cardiovascular health.
- Often seen in individuals with higher levels of HDL ("good cholesterol").
Lower Levels:
- Associated with an increased risk of cardiovascular diseases.
- May indicate conditions like Tangier disease or familial hypoalphalipoproteinemia.
How is the Apolipoprotein A1 Test Done ?
The Blood Sample for Apolipoprotein A1 Test is taken in following steps:
- The area where the needle will be inserted to take your blood is cleaned with an antiseptic alcohol wipe. The hollow on the inside side of the elbow or the tip of the finger are the most common sites for this.
- A tourniquet or a band is tied around your upper arm to facilitate the access to the vein in your arm.
- A needle is used to puncture your vein. The blood sample is collected into a test tube attached to the needle. The needle may cause a small pinch or sting when it is inserted.
- Once the vial or test tube is filled, the blood sample collection for the test is finished and the needle is taken out.
- Finger pressure is applied on the puncture site to stop the bleeding and the band aid is applied at the site.
How to Schedule an Apolipoprotein A1 Test with Dr. B. Lal Lab ?
- Go to the Dr. B. Lal Lab website.
- Go to the “Book a test” tab.
- Select the “Lab Test” tab.
- Type “Apolipoprotein A1 Test” in the search bar.
- Click on the test.
- The test page with all the test details will show up.
- Click on “Book Now”.
- Login and verify your mobile number with OTP.
- Now enter your details.
- Select date & time for booking a Apolipoprotein A1 Test in Jaipur.
- Check out.