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Test
test details

UNCONJUGATED ESTRIOL (E3) (CLIA)1 Observations included

MRP: ₹600

Recommended For

maleMalefemaleFemale
  • Age Group
    Age Group0-99 Years
  • Report Generation Time
    Report Generation Time29-05-2024 13:52:10
  • Sample Type
    blood sampleSerum
  • Collection At
    home visitHomelab flaskLab
Description

Estrogens are involved in development and maintenance of the female phenotype, germ cell maturation, and pregnancy.During pregnancy E3 becomes the dominant estrogen. The fetal adrenal gland secretes dehydroepiandrosterone-sulfate (DHEAS), which is converted to E3 in the placenta and diffuses into the maternal circulation. E3 levels increase throughout the course of pregnancy, peaking at term.Decreased second trimester uE3 has been shown to be a marker for Down and trisomy-18 syndromes. Low levels of uE3 also have been associated with pregnancy loss, Smith-Lemli-Opitz syndrome (defect in cholesterol biosynthesis), X-linked ichthyosis and contiguous gene syndrome (placental sulfatase deficiency disorders), aromatase deficiency, and primary or secondary fetal adrenal insufficiency.

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