Sex Hormone Binding Globulin (SHBG), a glycoprotein produced in the liver, is often measured to understand how much testosterone is accessible to the body’s tissues. Low SHBG levels are associated with conditions like hirsutism, acne vulgaris, and polycystic ovarian disorder. While total testosterone measures the overall hormone level, SHBG provides insight into the active, available testosterone, offering valuable information when symptoms suggest an imbalance.