DGP (ANTI DEAMINATED GLIADIN PEPTIDE (IgA & IgG))

Overview

Celiac disease (gluten-sensitive enteropathy, celiac sprue) results from an immune-mediated inflammatory process that occurs in genetically susceptible individuals following ingestion of wheat, rye, or barley proteins .Due to the possibilities of the highly specific and sensitive serological determination of IgA and IgG antibodies against DGP the invasive procedures of biopsies can be given up DGP antibodies titer has been proved to correlate very well with the morphological appearance of the mucosa of the upper intestine. It has been also documented that DGP antibodies level fall very quickly after a gluten free diet has begun and rise immediately after restoring gluten to the diet.