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Elevated values of VMA along with other catecholamine metabolites are suggestive of catecholamine secreting tumor like Neuroblastoma, Pheochromocytoma and other Neural crest tumors. VMA levels may also be useful in monitoring patients who are also treated.
Theophylline, chocolate, vanilla, bananas, alcoholic drinks, tea, coffee, nicotine, and vigorous activity should be rigorously avoided by the patient for at least 72 hours prior to and during specimen collection.