Guinea pig urine, saliva, dust, dander and fur are more intense extracts compared with entire pelt, defecation, and serum. Since the size of airborne particles obtained from guinea pig urine and dander are very minute, it can easily enter the lower respiratory tract and cause allergic symptoms. Allergic sensitization and reactions to guinea pig (Cavia porcellus) have been well documented in laboratory animal handlers, primarily manifesting as rhinitis, conjunctivitis, and asthma.