Respiratory syncytial virus (RSV), is a member of the family Paramyxoviridea, it is an enveloped virus with a single stranded positive sense RNA genome. IgG RSV antibodies were of higher prevalence and at higher levels in the control group when compared to the infected case group (P < 0.001), indicating an important role for IgG antibodies in protection. To assess infection before recruitment, IgA RSV antibodies were also measured by MFAT. Risk factors for infection with RSV in children and young infants include low birth weight, young age of less than 6months, congenital heart disease, and Immunodeficiency/immuno-supression.