Myasthenia gravis (MG) is characterised by muscle weakness & easy fatigability most commonly due to autoantibody mediated loss of functional acetylcholine receptors. ACHR antibodies are not found in Congenital MG. This assay is used to diagnose Acquired forms of MG (90% positive), for detecting subclinical MG in recipients of D-penicillamine, Thymoma without clinical evidence of MG & Graft versus Host disease. It may also be positive in Lambert-Eaton myasthenic syndrome, Autoimmune liver disease & Paraneoplastic autoimmune neurological disorders.
Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling. This assay should not be requested for patients who have recently received radio-isotopes therapeutically or diagnostically due to potential assay interference.
Download the free health test app from Dr. B. Lal Clinical Laboratory. Find all the healthcare information and needs you require in just one place. You can schedule home collection, see reports, save medical history, search for more than 1800 tests, and more with just one app. Available both on iOS and Android. Simplify healthcare, download the Dr. B. Lal Clinical Lab App.