PROTHROMBIN (FACTOR II) MUTATION

Requirements

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    Sample Required EDTA Blood

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    Preperations Required Duly filled Genomics Clinical Information Requisition Form is mandatory.

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    Gender Male & Female

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    Age Group 0 - 99 Years

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    Collection AtHome & Lab

5200
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    1 Observations included

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PROTHROMBIN (FACTOR II) MUTATION

Observations Included

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10,000+ Tests Done

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Overview

The Prothrombin (Factor II) gene 20210G>A mutation is associated with elevated prothrombin. Higher concentrations of prothrombin lead to increased rates of thrombin generation, resulting in excessive growth of fibrin clots. Heterozygosity for 20210G>A is associated with a 3-fold increased risk of venous thrombosis. Affected individuals may be candidates for antithrombotic prophylaxis.

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