Overview
Prothrombin time is used to identify a deficiency of one or more of the clotting factors of the extrinsic coagulation system (I, II, V, VII, X) due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific factor inhibitor. Monitoring patients on oral anticoagulant therapy to maintain a patient in a safe therapeutic range.The prothrombin time is also reported as the INR (International Normalized Ratio), based on the ISI (International Sensitivity Index) Draw 6 mL of whole blood in 2 blue-top (Sodium Citrate) tube and gently mix by inverting. Transport the sample to the lab within 4 hours. If this isn’t possible, prepare PPP within 1 hour: First, centrifuge the sample at 3600 rpm for 15 minutes, then transfer the supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for another 15 minutes, and transfer the final supernatant (PPP) into a LABELED, clean plastic screw-capped vial. FREEZE IMMEDIATELY and ship FROZEN. DO NOT THAW.
What is Prothrombin Time Test ?
Prothrombin Time test is used to identify a deficiency of one or more of the clotting factors of the extrinsic coagulation system (I, II, V, VII, X) due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific factor inhibitor. Monitoring patients on oral anticoagulant therapy to maintain a patient in a safe therapeutic range. The prothrombin time test is also reported as the INR (International Normalized Ratio), based on the ISI (International Sensitivity Index).
What is the Purpose of Prothrombin Time Test ?
- Check the effectiveness of Anticoagulants: If you take the blood thinner warfarin, your prothrombin time is often monitored. The prothrombin time is presented in this case as an international normalized ratio (INR). In case your blood clotting ability is a concern, your doctor might suggest a prothrombin time test prior to surgery.
- Check for Liver condition: To investigate liver disease, the prothrombin time test may also be performed. It is amongst one of several exams used to screen liver transplant candidates. The model for end-stage liver disease (MELD), which is the name of this screening, is a scoring system used to determine the severity of chronic liver disease.
- For Preliminary Testing: You may require additional testing to confirm your condition if your doctor believes you may have additional health issues, such as liver problems or a bleeding disorder.
- MakeSurgical Plans: Before surgery, your surgeon might check that your blood is clotting normally to make sure you won't lose too much blood.
- Diagnose clotting and bleeding issues: PT tests assist medical professionals in identifying potential causes of excessive blood loss. Certain symptoms, such as heavy nosebleeds, cuts that don't stop bleeding, or unexplained or frequent bruises, can be explained by making a diagnosis for these conditions.
When is a Prothrombin Time Test Recommended ?
If you have or suspected to have following conditions, then Prothrombin Time Test is advised:
- Liver Disease
- Vitamin K Deficiency
- Bleeding Disorders
- Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE)
- Disseminated Intravascular Coagulation (DIC)
- Pre-surgical Screening
- Chronic Kidney Disease
Preparation for Prothrombin Time Test
- Unless otherwise directed by your doctor, there is no need for you to make any special preparations before the prothrombin time test.
- Other blood tests can be carried out in addition to a PT. If your doctor advises you to have multiple tests at once, they may ask you to fast for a specific period of time prior to a blood test.
- Drink adequate water before sample collection.
- Avoid vigorous physical activity before the sample collection.
- Follow the preparatory instructions as guided by your doctor.
What is the Cost of Prothrombin Time Test ?
The Price of a Prothrombin Time Test is Rs. 250. However, cost of the test may fluctuate depending on following factors:
- Other tests advised along with prothrombin time test
- Offers or discounts
- Empanelment of the patient
Components of Prothrombin Time Test
- Patient Plasma: This blood sample is being tested to find out how long it takes for a clot to form, which indicates how well the person's blood can clot.
- Mean Normal Prothrombin Time (MNPT): The standard clotting time of the general population, against which the patient's clotting time is assessed.
- Prothrombin Ratio (PR): The patient's Prothrombin Time to MNPT ratio, which suggests possible clotting anomalies.
- International Normalized Ratio (INR): A standardized PR version that adjusts test variability in order to ensure consistent blood-thinning therapy monitoring among various labs.
Interpreting the Prothrombin Time Test Results
It is vital that you discuss the significance of your prothrombin time test results with your doctor. Your values and the value comparison to the laboratory's reference ranges will be examined by your doctor.
The normal ranges for PT/INR results are:
- 11 to 13.5 seconds
- INR of 0.8 to 1.1
- INR of 2.0 to 3.0 if you’re taking warfarin. (There are some conditions for which a higher or lower target PT range is desired)
Your blood clots more slowly than usual if your PT test result or INR level is high. If you are not taking warfarin, this may indicate a liver issue, bleeding or blood clotting disorder. A high score could also indicate insufficient vitamin K intake.
How is the Prothrombin Time Test Done ?
The Blood Sample for Prothrombin Time Test is taken in following steps:
- The area where the needle will be inserted to take your blood is cleaned with an antiseptic alcohol wipe. The hollow on the inside side of the elbow or the tip of the finger are the most common sites for this.
- A tourniquet or a band is tied around your upper arm to facilitate the access to the vein in your arm.
- A needle is used to puncture your vein. The blood sample is collected into a test tube attached to the needle. The needle may cause a small pinch or sting when it is inserted.
- Once the vial or test tube is filled, the blood sample collection for the test is finished and the needle is taken out.
- Finger pressure is applied on the puncture site to stop the bleeding and the band aid is applied at the site.
How to Schedule A Prothrombin Time Test with Dr. B. Lal Lab ?
- Go to the Dr. B. Lal Lab website.
- Go to the “Book a test” tab.
- Select the “Lab Test” tab.
- Type “prothrombin time test” in the search bar.
- Click on the test.
- The test page with all the test details will show up.
- Click on “Book Now”.
- Login and verify your mobile number with OTP.
- Now enter your details.
- Select date & time for booking prothrombin time test in Jaipur.
- Check out.
+91 9166125555
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