Our body signals us when there is something amiss. One of the key signals physicians consider is CRP, or C-reactive protein. It is a liver product that appears when there is inflammation in the body. The measurement of CRP in the blood can inform physicians whether you have an infection, injury, or even risk for heart disease.
C-reactive protein (CRP) is a protein that increases in the blood when there is inflammation in your body. Inflammation is your body’s way of protecting itself from harm, like infection or injury. But too much or long-term inflammation can be a sign of a deeper problem, like heart disease, autoimmune disorders, or chronic infections.
Doctors suggest a CRP blood test to look for inflammation and to aid in diagnosing a number of conditions. It does not indicate precisely where the issue is, but it indicates something is occurring within your body.
The CRP normal range for the majority of healthy individuals is:
The high-sensitivity CRP (hs-CRP) test is sensitive enough to detect very low amounts of CRP. It is particularly useful in estimating your risk for heart attack and stroke.
The normal range for hs-CRP is:
If your hs-CRP level is high, it does not necessarily mean that you will develop a heart issue, but it informs your physician that you might need to get other heart-related risk factors like cholesterol and blood pressure checked.
It can help detect:
It assists your physician in determining whether further tests or treatments are necessary. It also assists in monitoring how well your body is reacting to treatment.
Physicians consider your CRP levels to determine what is happening in your body. Below is a basic CRP levels chart to outline it:
CRP Level (mg/L) | Meaning |
< 1 | Low risk of inflammation or cardiovascular disease (CVD) |
1 – 3 | Mild infection or moderate cardiovascular risk |
3 – 10 | Mild inflammation or possible viral infection |
10 – 100 | Bacterial infection, injury, or chronic inflammation |
> 100 | Severe infection, major trauma, or sepsis |
This chart is only a guideline. Your physician will use your symptoms, medical history, and other laboratory test results in making any diagnosis.
There are many factors that can raise CRP levels, including:
Low levels of CRP (usually less than 1 mg/L) are good. They show that you have little or no inflammation. A low CRP level does not rule out all health problems, especially those not related to inflammation. That is why CRP is just a part of the entire picture.
A CRP blood test is simple. A medical professional takes a small sample of blood from your arm, and it's sent to a lab for analysis. You usually don't need to fast before a CRP test unless your physician also ordered other blood tests like cholesterol.
Results usually take one or two days.
Doctors can order a CRP test if you have:
A high CRP level does not always mean serious disease. It can be due to a trivial infection or minor trauma. Your doctor will assess your symptoms and order further testing if needed.
To lower your CRP and inflammation:
Yes. Doctors often use the CRP test to follow patients with chronic disease. If you have inflammatory bowel disease or rheumatoid arthritis, your doctor may order CRP tests periodically to see how well the treatment is working.
A drop in CRP is typically a sign the inflammation is reducing, and your condition is improving.
CRP is just one of the markers of inflammation. Other tests include:
Your doctor can order these tests along with CRP for a complete picture.
There are home CRP test kits in some areas, but they are not common or necessarily reliable. It's best to have a laboratory where results can be properly interpreted by a doctor. Self-diagnosis of inflammation with CRP alone is not recommended.
So the next time your doctor orders a CRP test, remember, it's a simple test that can be a great source of information about what's happening in your body.