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The RPR/VDRL test is a blood test used to screen for syphilis, a sexually transmitted infection (STI). It detects antibodies produced by the body in response to the infection.
Fasting is usually not required before the RPR/VDRL blood test. You can eat and drink normally unless advised otherwise by your doctor.
A reactive or positive result may indicate a syphilis infection. However, confirmatory tests may be required because certain conditions can sometimes cause false-positive results.
Yes, in some cases conditions like autoimmune diseases, pregnancy, viral infections, or other medical conditions may lead to false-positive results. Additional testing helps confirm the diagnosis.
The test is performed by collecting a small blood sample from a vein in your arm. The procedure is quick, simple, and usually takes only a few minutes.
You may need this test if you have symptoms of syphilis, have had unprotected sexual contact, multiple partners, or if your doctor recommends routine STI screening.
Most laboratories provide RPR/VDRL test results within 24 to 48 hours, depending on the testing facility and location.
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Your doctor may recommend this test if you experience symptoms such as:
In early stages, syphilis may show very mild symptoms or none at all. Regular screening helps detect infection before complications occur.
| Result | Meaning |
| Non-Reactive / Negative | No antibodies detected |
| Reactive / Positive | Possible syphilis infection |
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